Fatal and non-fatal AIDS and non-AIDS events in HIV-1 infected patients with high CD4 counts
نویسندگان
چکیده
Results 10998 patients were included contributing 43524 person-years of follow-up (PYFU). The majority of followup (80%) was with a viral load ≤500, 12% between 50110000 and 8% >10000. 95%, 72% and 64% of the followup in each strata respectively was in patients who had started cART. 379 AIDS events (14 deaths) occurred. There was a lower incidence of AIDS events in patients with a viral load ≤500 (IR 0.69 per 100 PYFU, 95%CI 0.60-0.78) compared to a viral load >10000 (IR 2.38 per 100 PYFU, 95%CI 1.87-2.89). 532 non-AIDS events (131 deaths) occurred. Patients with a viral load ≤500 had an incidence of non-AIDS events of 1.50 per 100 PYFU (95%CI 1.36-1.64), and 1.43 per 100 PYFU (95%CI 0.961.89) when viral load >10000. As shown in Figure 1, after adjustment, patients with a viral load >10000 had a 3 times higher incidence of AIDS events than those
منابع مشابه
Immuno-Virological Discordance and the Risk of Non-AIDS and AIDS Events in a Large Observational Cohort of HIV-Patients in Europe
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